AlphaThera · Est. 2016

AlphaThera

Our mission is to make antibody labeling as simple and consistent as possible, giving scientists confidence in their bioconjugation reactions.

Label your antibody right out of the tube, no purification required with oYo-Link®. Site-specific labeling takes 30-sec hands on time. Label with Oligos, Biotin, Azide, Enzymes and more.

AlphaThera
AlphaThera logo
Photo: Unsplash
About the Partner

More About AlphaThera

AlphaThera was co-founded by Dr. Andrew Tsourkas and Dr. James Hui in 2016. Given the prevalent and critical roles of antibody in biomedical research and the limitations of the existing chemical conjugation methods, Drs. Tsourkas and Hui immediately saw the potential of oYo-Link® in helping countless scientists achieve their research goals.

Much of Dr. Tsourkas's early work revolved around the development of nanoparticles for use in the imaging and/or treatment of various diseases, including cancer, atherosclerosis, and autoimmune diseases. Scaling up these particles was severely limited by the low efficiency attachment of the targeting antibodies onto surfaces such as nanoparticles. The company's team of scientists and business leaders has since grown to engage the commercial space.

Born in the TITAN Lab

Dr. Andrew Tsourkas is a Professor of Bioengineering and Head of the Targeted Imaging, Therapeutics and Nanomedicine (TITAN) lab at the University of Pennsylvania.

Better Bioconjugation

New technologies to improve the efficiency of the bioconjugation reaction and control the orientation of proteins and antibodies on surfaces to maximize antibody activity.

Photoreactive Binding Domains

James Hui spearheaded the idea of using photoreactive antibody-binding domains to site-specifically label the heavy chain of Immunoglobulin G (IgG).

LASIC & oYo-Link®

These efforts produced the LASIC technology and the family of reagents now known as oYo-Link®.

Custom Services

Services Offered

Services We Provide

Choose from our range of oYo-Link labels including oligonucleotides, enzymes and fluorescent dyes & proteins, click chemistry, drugs, biotin and epitope tags. See our most popular services below or contact us to tell us more about your project requirements.