BioIVT Human Microsomes
- Liver
- intestine
- kidney or lung
- Pooled or individual donors
- Frozen
A major tool for studying metabolite ID, reaction phenotyping, intrinsic clearance and inhibition studies.
CYP and non-CYP enzymes, activity kits and antibodies for ADME and DMPK studies. Tell us the enzyme, species and format — our technical team checks our principal suppliers and comes back with availability and pricing.
Subcellular fractions, recombinant enzymes and inhibitors covered across our partners’ ranges.
Species listed are for BACTOSOMES®; other enzymes are mainly human.
Selected from our partners’ ranges for this category.
BioIVT A major tool for studying metabolite ID, reaction phenotyping, intrinsic clearance and inhibition studies.
Cayman Chemical A triazole antifungal agent (synonym R 41400).
Santa Cruz Biotechnology An inhibitor of CYP proteins, thromboxane synthetase and 5-LO.
BACTOSOMES® & recombinant enzymes
ADME-Tox specialist whose BACTOSOMES® are bacterial membranes carrying recombinant CYPs co-expressed with human NADPH-CYP reductase, with or without cytochrome b5.
CYP450 isoform-specific and FMO3 / aldehyde oxidase activity kits, SULT enzymes and CYP inhibitors.
CYP1A1 (B-2), CYP1A2 (D15), CYP3A (B-3), CYP2B1/2B2 (9.14) and other CYP antibodies, plus the non-CYP inhibitor disulfiram.
Enzymes and BACTOSOMES® ship frozen on dry ice; kits and antibodies ship cold-chain. Storage is on each datasheet.
Lead time depends on supplier stock and is confirmed with your quote.
Move enzymes to –80 °C straight away and thaw on ice just before use. Avoid repeated freeze–thaw.
INR pricing available. GST invoice provided with every order.
a single, defined enzyme shows exactly which pathway metabolises a drug — CYPs for Phase I oxidation, and non-CYP enzymes such as SULTs and UGTs for Phase II conjugation.