ReadyCell Barrier Models: Predicting Human Drug Absorption In Vitro
Understanding and optimizing intestinal absorption is critical for the success of orally administered drugs. Yet, predicting human permeability early in development remains a key ADME challenge. This scientific webinar brings together expert insights on leveraging ReadyCell’s Caco-2 and MDCK cell-based models to accurately simulate human intestinal barriers.
Learn how these in vitro platforms enable comprehensive assessment of passive diffusion, active transport, and efflux, guiding compound selection and formulation decisions. Through interpretation of Papp values, efflux ratios, and TEER measurements, participants will gain practical strategies to support BCS classification and de-risk IND-enabling studies. The session will also highlight real-world applications of ReadyCell’s barrier systems in lead optimization and early-stage ADME screening.
Speaker
Dr. Swati Chitrangi
Head of Product Management – ADME-Tox | Krishgen Biosystems
Dr. Swati Chitrangi is a highly accomplished life sciences leader with over 16 years of experience driving innovation at the intersection of drug discovery, ADME-Tox science, and strategic product management. Armed with a PhD in Biological Sciences and executive business training from IIM Lucknow, Dr. Swati blends deep scientific insight with strategic commercial acumen. Her expertise spans 3D cell culture systems, organoids, in vitro toxicology, and translational ADME platforms. She has held leadership and scientific roles at Advancells Group, Yashraj Biotechnology, and IIT Bombay, and conducted internationally recognized research at AIST, Japan. A sought-after speaker and thought leader, Dr. Swati regularly presents at prominent industry forums including CPHI, IMAPAC, ISSCR, and AIIMS Delhi.
Key Learning Objectives
- Discover ReadyCell’s ready-to-use models: CacoReady, CacoGoblet, PreadyPort & PreadyTake
- Predict drug absorption, efflux & transport mechanisms
- Analyze key data: Papp, TEER & Efflux Ratio
- Align studies with BCS & IND regulatory needs
- Learn from real-world case studies in drug discovery
Ideal for
- Researchers
- DMPK Scientists
- ADME-Tox Teams
- Formulation Experts
Watch Now: ReadyCell Barrier Models: Predicting Human Drug Absorption In Vitro
This webinar is available on demand. Fill in the form to watch the full recording — we'll email you the link too.
- August 29, 2025 · 2:00 to 3:00 PM
- Dr. Swati Chitrangi, Krishgen Biosystems
- kbiinfo@krishgen.com
- +91 22 49198700
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