Addressing In Vitro Eye Irritation With The SkinEthic HCE: Recent Developments and Live Lab Session

Validated and integrated in the OECD TG492 guideline, the SkinEthic HCE model replaces animal testing to identify products not requiring classification for eye irritation. The webinar presents the characterization of the model, its specificities, and the importance of quality control in manufacturing to deliver a high-performance model every week.

Its use within the OECD guidance on Integrated Approaches to Testing and Assessment (IATA) for serious eye damage and eye irritation is presented, along with the new perspectives opened by the ongoing validation of the Time-to-Toxicity method to identify mild irritants (category 3).